Early detection saves lives
Reliable results that you can trust
Our CancerDetect™ - Oral & Throat test detects molecular features of oral & throat cancers even in early stages when it is more treatable.
The test delivers the highest accuracy currently possible and surpasses the current standard of care - the visual and tactile exam.
Additional insights included with Oral Health Pro™
Provides a range of insights into oral health based on saliva, including:
The gum health score quantifies the abundance of microbial activities present in the oral cavity that may pose a risk to worsening/ or deterioration of your gums. The ability of these activities to chronically settle in the mouth depends on their properties, host defenses, and the composition of the oral microbiome. Chronic exposure to these microbial activities poses a risk for development of gingivitis and periodontitis, which can contribute to exacerbation of underlying conditions and also poses a risk for worsening oral health. A significant increase in these microbial activities signals an opportunity to address a dysbiotic microbiome and strengthen impaired host defenses.
The dental health score quantifies the abundance and expression of cariogenic and anti-cariogenic microbial species in the oral cavity. The data observed help identify microbial species which contribute to dental cavities. It also identifies cariogenic activities involved in carbohydrate metabolism, acid promotion, and chelation which would contribute to degradation of the teeth.
The Breath Odor Health score is an assessment of the microbiome balance with respect to malodor due to specific microbial activities from across Proteobacteria, Actinobacteria, Bacteroidetes, and Firmicutes. The microbial activities measured by this score are associated with malodorous compounds like polyamines and sulfur-containing molecules, as well as an acidic environment which augments the malodorous effect. A low Breath Odor Health score signals an opportunity to address a dysbiotic microbiome and improve breath conditioning.
The Pathobiont Health score indicates the accumulation of pathobionts in the oral cavity which may negatively impact health (see partial list of species on the next page). Pathobionts are microbial species (bacteria, fungi, or protozoa) that, under normal circumstances, either do not cause any harm or provide a benefit to the human host. However, they can become pathogenic (cause a disease) under certain environmental conditions, such as dysbiosis2. The ability of these pathobionts to accumulate and impact health depends on their properties, host defenses, and the composition of the oral microbiome. Chronic oral conditions, such as gingivitis and periodontitis, occur when the pathobionts are left unchecked, allowing them to flourish and negatively impact health. In some people, these oral conditions can progress to more severe systemic diseases, such as arthritis, heart disease, and Alzheimer’s. A significant increase in the pathobionts signals an opportunity to address a dysbiotic microbiome and strengthen impaired host defenses.
The fungal activity score quantifies the abundance of cancer-associated fungi (Candida, Malassezia, and certain species of Saccharomyces). The ability of these fungi to chronically settle in the mouth depends on their properties, host defenses, and the composition of the oral microbiome. Chronic fungal infections occur when one or more species are left unchecked, allowing them to flourish. Our data show that increased abundance of the fungi assessed in this score are associated with oral and throat cancer. A significant increase in these fungal species signals an opportunity to address a dysbiotic microbiome and strengthen impaired host defenses.
Within healthy oral microbiomes, Lactobacillus species are found in small quantities, while many Streptococcus species are detected in moderate quantities. When host defenses are impaired, these species accumulate to large quantities, and this increase is associated with microbial production of reactive oxygen species, formaldehyde, acetaldehyde, and acetoin. These compounds have genotoxic potential, and therefore, large quantities of these microbes may pose a health risk.
We provide personalized oral health treatment protocols that allow oral health professionals to customize their patients' oral care journey. Our treatment recommendations offer three support categories: Lifestyle and Oral Hygiene support, Nutritional support, and Professional Treatment.
FDA breakthrough device
designation granted for accelerated review.
* This test is not an FDA-approved or cleared device
Our science sets us apart and is revolutionizing the future of early diagnostics
We employ our unique RNA analysis technology and breakthrough machine learning techniques to accurately discover the interactions between microbial activities and human gene expression in the progression of oral diseases and cancer.
This allows us to reimagine comprehensive oral care with our groundbreaking early detection test and empower patients everywhere with a convenient and accessible early testing solution.